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THE VIRILITY SOLUTION: MODERN METHODESOF CURESPenile injection therapy came about by chance. In 1980, the French physician Ronald Virag reported that during surgery on the penis, he inadvertently injected an anesthetized patient in the wrong part of the penis with papaverine, a nitrogen-containing substance derived from the opium poppy. The resulting relaxation of the smooth muscle of the penile arterial walls created an unexpected two-hour erection. The mistake by Virag set in motion serious research into the use of injectable medication for relief of ED. At around the same time, Giles Brindley a British physiologist and research scientist, found that when the drug phenoxybenzamine was injected directly into the corpora cavernosa of the penis, an erection could be produced within a few minutes. Still, even though it was a powerful substance, phenoxybenzamine had serious side effects, including cardiac arrhythmia, nausea, and hyperventilation. Additionally, it was found to be carcinogenic in test animals. In 1984, in Paris, a New York urologist, Dr. Adrian Zorgniotti, presented his first case studies of self-injection using a dual combination of papaverine and phentolamine. The latter drug interrupts the passage of neurotransmitters, which then causes relaxation of the smooth muscles of the penis. Two years later, Japanese researchers presented evidence that injections of prostaglandin E-l produced powerful erections. Finally, modern medicine had injectable drugs that, used either alone or in combination, were able to give a man an erection whenever he wanted one. Slowly, news of the favorable results with the injectable medication began to spread within the small international community of urologists who were treating ED. Most began utilizing all three—papaverine, phentolamine, and prostaglandin E-l—in what was referred to as “tri-mix.” *17\183\8* Related Posts:Tags: Men’s Health Leave OneYou must be logged in to post a comment. |
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